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单胞体和双胞体种群的进化揭示了非家庭环境中常见的,强大的和可变的多胞体效应

Vivian Chen¹, Milo S Johnson^2,3,4, Lucas Hérissant⁵

¹Department of Biology, Stanford University, Stanford, United States.

|October 20, 2023

概括

环境的变化表明,有益的突变往往具有不可预测的副作用 (变性). 酵母菌进化研究表明,这些影响在不同的条件下有所不同,但相同基因的突变具有相似的影响,性影响适应途径.

科学领域:

进化生物学是进化的生物学.
遗传学遗传学是一个
微生物学微生物学

背景情况:

生物通过有益的突变适应环境.
环境是动态的,当有机体面临新的条件时,这会带来挑战.
单一突变影响多个特征的变性,可以影响新环境中的适应成功.

研究的目的:

为了调查适应性突变的类效应的发病率和性质.
了解类效应在不同的环境中是如何变化的.
为了检查 ploidy (haploid 与 diploid) 对适应性突变光谱的影响.

主要方法:

在多个环境中进化了带条码的平分类和二分类发芽酵母种群.
从已进化的种群中分离出适应性克隆.
评估了在非家庭环境中发现的适应性突变的适应性影响.

主要成果:

Pleitotropy 是常见的,大多数适应性突变在非家庭环境中表现出适应性效应.
类效应在很大程度上是不可预测的,在某些环境中是有益的,在其他环境中是有害的.
同一个基因内的突变倾向于表现出类似的类效应.
排列性以特定条件的方式影响适应性突变模式,在某些条件下,不同的基因组会在单体和双体中受到影响.

结论:

适应性突变常常会带来类的后果,这些后果可以根据环境有益或有害.
虽然整体而言,类效应是不可预测的,但它们在相同基因的突变中表现出一些一致性.
排卵性是塑造适应环境压力的遗传基础的一个重要因素.

关键词:

它们中的一种是S. cerevisiae.进化演化演化演化演化演化演化演化进化生物学是进化的生物学.遗传学遗传学遗传学是一个基因组学就是基因组学.类型的类型.权衡权衡权衡权衡权衡权酵母酵母是一种酵母.

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