来自中国北部的健康成年人生物化学分析物的参考间隔:基于人口的横截面研究
Siming Jia1,2,3,4,5, Liu Wei6, Xiaoying Shi7
1Trauma Emergency Center, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, People's Republic of China.
Medicine
|October 20, 2023
概括
这项研究为中国北部的生物化学分析物建立了特定年龄和性别的参考间隔. 这些参考间隔 (RIs) 对于准确的实验室测试至关重要,并且在不同的人口群体中显示出显著的差异.
科学领域:
- 临床生物化学 临床生物化学
- 实验室医学 实验室医学
- 人口健康 人口健康
背景情况:
- 参考间隔 (RIs) 对于解释实验室测试结果至关重要.
- 现有的RI往往缺乏针对不同人群的特异性,导致潜在的误诊.
- 地理和人口的变化需要特定区域的RI.
研究的目的:
- 确定生物化学分析物的特定年龄和性别的参考间隔.
- 在中国北部的石家庄建立一个健康人口的RI.
- 为该地区准确的临床实验室测试提供基础.
主要方法:
- 一项涉及42,979名健康个体的横截面研究.
- 生物化学分析剂使用贝克曼·科尔特AU5800分析仪进行测量.
- 分析了数据,以建立特定年龄和性别的参考间隔.
主要成果:
- 生物化学分析物的综合年龄和性别特异性RI已建立.
- 在不同年龄和性别群体中观察到分析剂水平的显著差异 (P < .001).
- 分析剂水平显示了受年龄和性别影响的动态变化.
结论:
- 该研究为中国北部提供了关键的,特定于人口的参考间隔.
- 这些RI对于在临床实践中准确解释生物化学试验至关重要.
- 经过验证后,当地临床实验室可以采用确定的间隔.
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