脂肪酸概况与男性腹部肥胖的关联
V S Shramko1, L V Shcherbakova2, E V Kashtanova2
1Research Institute of Internal and Preventive Medicine - Branch of Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia. nosova@211.ru.
Bulletin of experimental biology and medicine
|October 20, 2023
概括
患有腹部肥胖的男性表现出更高水平的特定omega-6和omega-3不和脂肪酸. 玛-烯酸水平与增加患腹部肥胖的几率直接相关.
科学领域:
- 生物化学 生物化学
- 人体生理学 人体生理学
- 营养科学 营养科学
背景情况:
- 腹部肥胖是一种与代谢障碍相关的重大健康问题.
- 了解特定脂肪酸在肥胖中的作用对于制定有针对性的干预措施至关重要.
研究的目的:
- 调查血不和脂肪酸水平与中年男性腹部肥胖之间的关联.
- 为了确定可能作为腹部肥胖的生物标志物的特定脂肪酸.
主要方法:
- 使用高性能液态染色学 (HPLC) 分析了血脂肪酸概况.
- 腹部肥胖是根据腰围标准 (>94厘米) 诊断的.
- 统计分析包括ROC分析和回归分析.
主要成果:
- 患有腹部肥胖症的男性表现出omega-6 (γ-linolenic, dihomo-γ-linolenic) 和omega-3 (eicosapentaenoic, docosahexaenoic) 脂肪酸的水平较高.
- 腹部肥胖与较高的甘油三,葡萄糖和较低的HDL胆固醇有关.
- 玛-烯酸水平与腹部肥胖的可能性有直接关联.
结论:
- 特定的不和脂肪酸,特别是γ-烯酸,与男性的腹部肥胖有关.
- 这些脂肪酸可能是早期检测或腹部肥胖风险评估的潜在生物标志物.
相关概念视频
Cholesterol: Significance and Regulation
560
Although not a source of energy, cholesterol plays a significant role as a foundational structure for bile salts, steroid hormones, and vitamin D, as well as being a crucial component of plasma membranes. Approximately 15% of blood cholesterol is derived from our diet, with the remainder synthesized from acetyl CoA by the liver and intestines. Cholesterol is eliminated from the body through its conversion into bile salts, which are eventually discarded in the feces.
Considering cholesterol and...
Considering cholesterol and...
560
Obesity
510
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
510
Overview of Fatty Acid Metabolism
30.7K
Lipids also are sources of energy that power cellular processes. Like carbohydrates, lipids are composed of carbon, hydrogen, and oxygen, but these atoms are arranged differently. Most lipids are nonpolar and hydrophobic. Major types include fats and oils, waxes, phospholipids, and steroids.
Fatty acids are catabolized in a process called beta-oxidation, which takes place in the matrix of the mitochondria and converts their fatty acid chains into two-carbon units of acetyl groups. The acetyl...
Fatty acids are catabolized in a process called beta-oxidation, which takes place in the matrix of the mitochondria and converts their fatty acid chains into two-carbon units of acetyl groups. The acetyl...
30.7K
Overview of Lipid Metabolism
1.7K
Lipid metabolism is a crucial process in the human body that involves the synthesis and degradation of lipids. This process is essential for energy production, cell membrane formation, and hormone production, among other functions.
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
1.7K
Hypodermis
4.6K
The hypodermis (the subcutaneous layer or superficial fascia) is present directly below the dermis. It connects the skin to the underlying fascia (fibrous tissue) of the bones and muscles. It is not strictly a part of the skin, although the border between the hypodermis and dermis can be difficult to distinguish. The hypodermis consists of well-vascularized, loose, areolar connective tissue and adipose tissue, which functions as a mode of fat storage and provides insulation and cushioning for...
4.6K
Structure of Lipids
88.4K
Lipids include a diverse group of compounds that are largely nonpolar in nature. This is because they are hydrocarbons that include mostly nonpolar carbon-carbon or carbon-hydrogen bonds. Non-polar molecules are hydrophobic (“water fearing”), or insoluble in water. Lipids perform many different functions in a cell. Cells store energy for long-term use in the form of fats. Lipids also provide insulation from the environment for plants and animals. For example, they help keep aquatic...
88.4K


