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在BATF中抑制BIM以维持在外围的耐受性T细胞

Philip J Titcombe1, Milagros Silva Morales1, Na Zhang1

  • 1Department of Medicine, Center for Immunology, University of Minnesota Medical School, Minneapolis, MN, USA.

The Journal of experimental medicine
|October 20, 2023
PubMed
概括

转录因子BATF驱动T细胞能量,这是一个关键的外围耐受机制. 在长时间暴露于抗原时,其缺失导致T细胞缺失和调节性T细胞 (Tregs) 的丧失.

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