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Updated: Jul 12, 2025

Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice
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Published on: June 12, 2021

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在癌症中,BCL6通过对抗BLIMP1促进了类似干细胞的CD8+ T细胞程序

Qinli Sun1, Dongli Cai2,3, Dingfeng Liu2,3

  • 1Institute for Immunology and School of Medicine, Tsinghua University, Beijing 100084, China.

Science immunology
|October 20, 2023
PubMed
概括

BCL6 抑制来自原生细胞 (Tprog细胞) 的强有力的细胞毒性 CD8+ T 细胞 (Tterm细胞) 的发展. 向TGF-β-BCL6和IL-2-BLIMP1通路可能会提高癌症免疫治疗的持续性和有效性.

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