一个前极-时间电路决定了社会信息对的决策影响
Ali Mahmoodi1, Caroline Harbison1, Alessandro Bongioanni2
1Wellcome Centre for Integrative Neuroimaging, Department of Experimental Psychology, University of Oxford, Oxford, UK.
灵长类动物平衡个人经验和社会线索,以做出最佳选择. 背中前极皮质 (dmFPC) 有助于衡量社会信息的可靠性,指导行为适应.
科学领域:
- 神经科学是一个神经科学.
- 灵长类的认知能力
- 决策 - 决策 - 决策 - 决策
背景情况:
- 灵长类动物结合个人经验和社会信息来做出选择.
- 两种信息来源的可靠性各不相同,需要灵活的行为调整.
- 背中前极皮质 (dmFPC) 和中上状 (mSTS) 都参与处理社会信息.
研究的目的:
- 研究dmFPC在调节基于其可靠性的社会信息使用中的作用.
- 阐明dmFPC活动与mSTS在基于社会线索的指导行为中的相互作用.
- 确定dmFPC和mSTS对灵活使用社会信息的因果关系.
主要方法:
- 用过膜超声波刺激 (TUS) 来对的dmFPC活性进行可逆性破坏.
- 在决策任务期间记录神经活动和行为反应.
- 对比了dmFPC中断与mSTS中断对社会信息使用的影响.
主要成果:
- 破坏dmFPC功能会影响利用可靠的社会信息的能力,同时增加对不可靠的社会线索的依赖.
- 破坏mSTS均地减少了社会信息对行为的影响,不管可靠性如何.
- dmFPC活动表现出与mSTS的特定交互模式,这对于适应性社会学习至关重要.
结论:
- 在评估社会信息可靠性和灵活指导行为方面,dmFPC起着至关重要的作用.
- 在社会环境中,dmFPC-mSTS互动对于适应性决策至关重要.
- 针对dmFPC的神经调节提供了对社会认知的神经机制的洞察.
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