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剖腹产和生育能力之间的关系:基于人口的队列研究
Yeneabeba Tilahun Sima1, Maria Christine Magnus2, Liv Grimstvedt Kvalvik1
1Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.
American journal of obstetrics and gynecology
|October 20, 2023
概括
剖腹产与较低的生育能力和较高的不孕症风险有关. 怀孕时间较长的女性也面临着剖腹产的更高风险,这表明存在复杂的关系.
科学领域:
- 生殖健康 生殖健康
- 产科 产科 产科 产科 产科
- 流行病学 流行病学
背景情况:
- 之前的研究表明,剖腹产与随后的怀孕减少之间存在相关性.
- 剖腹产在生育能力较低的妇女中更为普遍,但因果关系尚不清楚.
研究的目的:
- 为了研究剖腹产分娩和生育能力之间的双向关系.
- 确定剖腹产是否影响女性怀孕的能力,以及是否降低生育能力增加了剖腹产的可能性.
主要方法:
- 使用挪威母亲,父亲和儿童队列研究以及挪威医疗出生登记处的数据进行前性队列研究.
- 根据42,379名妇女之前的分娩方式估计的生育率和不孕症风险.
- 在74,024名妇女的受精能力 (受孕时间) 基础上评估了剖腹产风险.
主要成果:
- 与阴道分娩相比,先前剖腹产的妇女患不孕症的风险增加了21%,生育能力比率降低了10%.
- 与那些在2个周期内怀孕的女性相比,需要12个或更多周期才能怀孕的女性患剖腹产的风险高出57%.
- 这些关联在调整混因素后,在等价组中持续存在.
结论:
- 在剖腹产分娩和生育能力之间存在双向关系.
- 前经过剖腹产的妇女表现出更低的生育能力和更高的不孕症风险.
- 降低生育能力与剖腹产的可能性增加有关,这表明潜在的共同潜在因素,而不是手术本身的直接原因.
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