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Updated: Jul 12, 2025

A Method for Determination and Simulation of Permeability and Diffusion in a 3D Tissue Model in a Membrane Insert System for Multi-well Plates
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开发一种塔达拉菲尔通过皮肤的配方,并评估其在体外通过皮肤透的能力,使用Strat-M®膜

Jeong Sun Sohn1, Jin-Seok Choi2

  • 1College of General Education, Chosun University, Gwangju 61452, Republic of Korea.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
|October 20, 2023
PubMed
概括

这项研究开发了一种新的tadalafil (TDF) 透皮配方,增强其溶解性和皮肤透性. 优化的配方表现出稳定性和改善了用于外部使用的药物输送潜力.

关键词:
双乙烯甘醇是一种二基醇.在HDTMA-Br中使用.在体外通过皮肤的透性试验.稳定的稳定性 稳定的稳定性在Strat-M®膜上塔达拉菲尔 (tadalafil) 是一个药物.

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相关概念视频

Methods for Studying Drug Absorption: In vitro01:16

Methods for Studying Drug Absorption: In vitro

In vitro experiments are crucial for understanding the transport and absorption of drugs through biological materials. These studies employ varied methods such as the diffusion cell method, the everted sac technique, and the everted ring technique.
The diffusion cell method uses a two-compartment cell, including a donor compartment with the drug solution, which simulates the environment where the drug is applied, and a receptor compartment with a buffer solution, which simulates the environment...
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