基线光学连贯性断层扫描血管图的关联与在预周周长格劳科马眼睛中出现眼性视野缺陷的发展
Jin Yeong Lee1, Joong Won Shin2, Anna Lee1
1Department of Ophthalmology, Asan Medical Center, Seoul, Korea (the Republic of).
The British journal of ophthalmology
|October 20, 2023
概括
通过光学连贯断层扫描血管学 (OCT-A) 测量的下基线下部时血管密度 (VD) 预测了前周周边绿内障 (PPG) 患者的视野 (VF) 缺陷以及随着时间的推移更快的VF损失.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼研究研究 玻璃眼研究
- 光学连贯性断层扫描血管学
背景情况:
- 偏偏偏偏光眼 (PPG) 的特点是视神经受损而没有可检测的视野缺陷 (VF).
- 早期发现青光眼的进展对于及时干预和维护视力至关重要.
- 光学连贯断层扫描血管学 (OCT-A) 提供了一种非侵入性方法来评估视网膜微血管.
研究的目的:
- 为了确定OCT-A的基线血管密度 (VD) 参数是否可以预测PPG患者中眼性VF缺陷的发展.
- 调查基线OCT-A衍生的VD与PPG中VF敏感性丧失的速度之间的关联.
- 评估OCT-A参数对青光瘤进展的预测值.
主要方法:
- 在200名PPG患者的回顾性分析中,标准自动化周长度正常,并且在基线时进行了OCT-A.
- OCT-A用于测量环囊性静脉疾病 (cpVD) 和副/周静脉疾病.
- 考克斯比例危险模型和线性回归被用来评估OCT-A参数对VF缺陷和VF损失率的预测能力.
主要成果:
- 在长达3.1年的随访期间,9.0%的眼睛出现了眼性VF缺陷.
- 在基线下,较低的下神经纤维层和较薄的下视网膜神经纤维层 (RNFL) 预测了玻璃眼性VF损失.
- 较低的下部cpVD和RNFL厚度与更快的全球VF敏感性损失率有关.
结论:
- 一个较低的基线下部部cpVD是一个显著的预测者,在PPG中发展眼性VF缺陷.
- 较低的下心血管疾病与PPG中全球VF敏感性损失的加快速度有关.
- 来自OCT-A的VD参数,特别是在部下部区域,有潜力用于早期青光眼的进展监测.
更多相关视频
相关概念视频
Glaucoma: Overview
599
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
599
Open Angle Glaucoma: Treatment
459
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
459
Angle Closure Glaucoma: Treatment
536
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
536


