用孕激素逆转药物堕胎:一个系统的审查
Bianca Maria Stifani1, Antonella Francheska Lavelanet2
1Department of Obstetrics & Gynecology, Westchester Medical Center / New York Medical College, Valhalla, New York, USA bianca.stifani@wmchealth.org.
BMJ sexual & reproductive health
|October 20, 2023
概括
在米费普里斯顿之后使用孕激素来逆转药物流产并没有得到强有力的证据支持. 研究表明,与单独使用米费普里斯相比,持续怀孕率相似,数据质量不佳,安全性问题存在.
科学领域:
- 生殖健康 生殖健康
- 药理学 药理学是指药理学的学科.
背景情况:
- 评估孕激素在寻求继续怀孕的个体逆转mifepristone的效果方面的疗效.
- 评估前激素干预药物在mifepristone后的现有证据基础.
结论:
- 目前的证据,在很大程度上质量不佳,并没有显著地支持与单独的米费普里斯顿相比,更高的孕持续怀孕率.
- 在RCT中的案例系列和安全问题中的方法论和道德问题需要谨慎.
- 需要进一步进行高质量的研究,以最终评估孕激素在药物堕胎逆转中的作用.
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