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磁共振弹性扫描在肝脏铁过载患者的技术成功和可靠性

Jingjing Liu¹, Mengyue Huang¹, Yong Zhang¹

¹Department of MR Imaging, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China (J.L., M.H., Y.Z., F.Y., X.Z., J.C.).

Academic radiology

|October 20, 2023

概括

旋回回声磁共振弹性图 (MRE) 是一种可靠的方法,用于测量轻度至中度铁过载时的肝硬度. 对于严重的铁过载,旋回回声MRE是首选的,而不是旋回回声平面成像MRE.

科学领域:

医疗成像医学成像
肝病学肝病学是一种肝病学.
生物物理学的生物物理.

背景情况:

肝脏的铁过载可能会导致易感元件,使使用磁共振弹性学 (MRE) 复杂化肝硬度测量.
准确的肝硬度评估对于管理肝脏疾病至关重要,包括与铁过载相关的肝脏疾病.

研究的目的:

评估两个肝脏MRE序列在不同程度的肝脏铁过载患者的技术成功率和硬度测量可靠性.
为了比较旋回回声 (SE) MRE和旋回回声平面成像 (SE-EPI) MRE在铁过载引起的易感性人工物背景下.

主要方法:

对37名铁过载肝脏患者的回顾性审查,通过R2*值证实.
2D SE MRE和2D SE-EPI MRE在四个铁过载类别 (轻度,中度,重度,极度重度) 的成功率,质量评分和肝硬度测量方面的比较.
斯皮尔曼的相关性分析,以评估R2*值和肝硬度之间的关系.

主要成果:

对于SE MRE和SE-EPI MRE的总体成功率分别为91.89%和78.38%. 对于严重的铁过载,率分别为100%和78.57%.
对于SE MRE,MRE质量得分为54,对于SE-EPI MRE则为48 (P=0.107).
在轻度,中度和重度铁过载 (P>0.6) 的两种MRE方法之间,没有发现肝硬度测量的显著差异. 两种方法的R2*值都没有显著影响度测量 (相关系数<0.1,P>0.6).

结论:

无论是SE MRE还是SE-EPI MRE,都能在轻度到中度的肝脏铁过载中,成功和可靠地测量肝硬度.
与SE-EPI MRE相比,SE MRE可能是评估严重肝脏铁过载时肝硬性的更好选择,因为其成功率更高.

关键词:

铁过载是因为铁过载.磁共振弹性图 (MRE) 是一种磁共振弹性图.

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