埃夫马罗多科金α (IL-22Fc) 的种群药理动力学和药理动力学

Yanke Yu1, Michael E Rothenberg2, Han Ting Ding2

  • 1Genentech, Inc., 1 DNA Way, South San Francisco, CA, 94080, USA. yu.yanke@gene.com.

概括

在182名受试者中分析了efmarodocokin alfa (IL-22Fc) 药理动力学和REG3A生物标志物变化. 人口PK/PD模型确定了影响efmarodocokin alfa暴露和REG3A反应的共变量,特别是在IBD患者中.

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