在补偿性生长过程中,银的营养代谢变化和调节
Jiabao Hu1,2,3,4, Youyi Zhang1,3,4, Kaiheng Yan1,3,4
1School of Marine Sciences, Ningbo University, Ningbo, China.
Marine biotechnology (New York, N.Y.)
|October 20, 2023
概括
在饥饿和重新养14天后,银色鱼表现出完全的补偿生长. 在饥饿期间,营养代谢从碳水化合物和脂质转变为蛋白质,在重新养时逆转为快速生长.
科学领域:
- 水产养殖是水产养殖的一种方式.
- 鱼类生理学 鱼类生理学
- 营养物质的新陈代谢
背景情况:
- 补偿生长 (CG) 对鱼类水产养殖至关重要,但其营养调节的理解不足.
- 银色 (Pampus argenteus) 需要优化的饥饿和再食协议以实现高效的生长.
研究的目的:
- 为了阐明完整的补偿生长模型,在银色的Pomfret.
- 为了研究营养代谢和基因表达过程中CG在银 pomfret.
主要方法:
- 涉及对照组和饥饿/再养组的比较研究 (14天的饥饿/14天的再养被认为是最佳的).
- 肌肉组织的非向代谢和转录组分析.
- 在饥饿和再养期间检查关键营养代谢调节基因.
主要成果:
- 饥饿优先使用碳水化合物和短链脂质,其次是蛋白质和长链脂质.
- 重新养导致最初的脂质积累以快速生长,然后蛋白质恢复.
- 饥饿增加了代谢基因表达 (例如,TSC2,MLYCD) 并促进了AMPK通路,同时在没有AMPK抑制的情况下重新养高调的合成基因.
结论:
- 在饥饿和重新养期间,银色鱼利用不同的能源来补偿生长.
- 基因表达模式,特别是涉及AMPK通路的基因表达模式,是CG期间营养代谢的关键调节者.
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