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Updated: Jun 9, 2026

Single-cell Gene Expression Using Multiplex RT-qPCR to Characterize Heterogeneity of Rare Lymphoid Populations
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Single-cell Gene Expression Using Multiplex RT-qPCR to Characterize Heterogeneity of Rare Lymphoid Populations

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在单细胞RNA测序数据中测量细胞对细胞表达变异性:对比分析和B细胞衰老的应用

Huiwen Zheng1, Jan Vijg2,3, Atefeh Taherian Fard4

  • 1Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD, Australia.

Genome biology
|October 20, 2023
PubMed
概括

本研究评估了使用单细胞RNA测序 (scRNA-seq) 数据测量细胞对细胞基因表达变异性的统计方法. 扫描仪表表现出卓越的性能,揭示了B细胞分化和衰老过程中的关键基因特征.

关键词:
衰老的衰老 衰老的衰老B 淋巴细胞分化分化细胞对细胞的变异性.评估框架 评估框架一个单细胞RNA-seqq.

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相关概念视频

Ribosome Profiling02:24

Ribosome Profiling

Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique helps...