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酸暴露会损害骨肌肉功能和Ca2+信号传递:对杜氏肌肉衰竭病理学的影响

Thomas A Lea1, Peter M Panizza1, Peter G Arthur2

  • 1School of Human Sciences, University of Western Australia, Perth, Western Australia, Australia.

The Journal of physiology
|October 21, 2023
PubMed
概括

低酸 (HOCl) 损害了杜申肌肉发育不良 (DMD) 的骨肌肉功能和信号传递. 这种反应性氧化剂在衰变肌肉中升高,可能会将炎症和氧化应激联系起来,为DMD提供潜在的治疗点.

关键词:
在Ca2+中.杜申尼肌肉发育不良症是什么含有高酸的低酸.这是一种炎症炎症炎症炎症.骨髓氧化酶是如何形成的中性粒细胞中性粒细胞.有活性氧物种的反应性氧物种.这是骨肌肉的骨架肌肉.

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