微生物对环境有毒物Ni (II) 和Co (II) 的影响:Paramecium中的关节毒性和细胞反应
Diana Laura Garza Amaya1, Alicia Thiel2, Melanie Möller1
1Molecular Cell Biology and Microbiology, Faculty of Mathematics and Natural Sciences, University of Wuppertal, Gausstraße 20, Wuppertal, 42119, Germany.
Chemosphere
|October 21, 2023
概括
(Ni) 和 (Co) 呈现出复杂的环境毒性. 细菌选择性地积累这些金属,影响它们的转移和对主要消费者Paramecium的毒性,影响早期的食物链.
科学领域:
- 环境科学 环境科学
- 生态毒理学 生态毒理学
- 微生物学 微生物学
背景情况:
- (Co) 和 (Ni) 是新兴的环境污染物.
- 了解它们对早期食物链的生态毒理影响至关重要.
研究的目的:
- 分析和在细菌和状植物Paramecium中的联合毒性和吸收机制.
- 为了研究从细菌转移金属到Paramecium,并确定毒性途径.
主要方法:
- 细菌和帕拉梅暴露于不同度的Co和Ni.
- 测量金属吸收量,毒性和热量层之间的转移.
- 对Paramecium进行转录分析,以确定分子反应.
主要成果:
- 比更有毒;联合暴露和缺乏食物细菌增加了毒性.
- 细菌选择性地积累金属,影响它们转移到Paramesium的比例.
- 与直接暴露相比,帕拉梅表现出明显的金属积累模式,表明细菌预积累.
- 转录组分析揭示了与运输,蛋白质降解和RONS压力有关的途径的放松调节.
结论:
- 细菌在食物链中的选择性金属预积累中发挥作用.
- Co和Ni在Paramecium中具有共同的毒性机制,解释了协同毒性.
- 环境受到CO和Ni的污染带来了复杂的生态毒理风险,受食物链动态的影响.
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