TP53

Alexa J Siddon1, Olga K Weinberg2

  • 1Department of Laboratory Medicine, Yale School of Medicine, 330 Cedar Street, PO Box 208035, New Haven, CT 06520, USA; Department of Pathology, Yale School of Medicine, 330 Cedar Street, PO Box 208035, New Haven, CT 06520, USA.

PubMed
概括

TP53基因突变显著影响骨髓质疏松综合征 (MDS) 和急性骨髓性白血病 (AML),影响疾病分类和患者的治疗结果. 了解这些遗传变异对于骨髓瘤癌的个性化治疗策略至关重要.