在HPV相关的口喉状状细胞癌中,在部剖析后,部痕感知
Vivienne H Au1, Lauren E Miller1, Margaret B Mitchell1
1Department of Otolaryngology - Head and Neck Surgery, Massachusetts Eye and Ear, Boston, MA, United States of America; Department of Otolaryngology - Head and Neck Surgery, Harvard Medical School, Boston, MA, United States of America.
American journal of otolaryngology
|October 22, 2023
概括
患有HPV+口腔状细胞癌 (OPSCC) 的患者通常报告部剖析痕对他们的生活质量的影响很小. 对痕影响的看法在各种患者和治疗因素中保持一致.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 生活质量研究 研究 生命质量研究
背景情况:
- 可见的部痕可能会影响患者的生活质量,但这在HPV+口腔状细胞癌 (OPSCC) 患者中尚未研究.
- 部解剖 (ND) 是HPV+OPSCC的常见程序,通常导致可见痕.
研究的目的:
- 评估患者对部痕的看法及其对生活质量 (QOL) 的影响,至少在HPV+OPSCC部剖析 (ND) 后6个月.
- 在这个特定的患者群体中探索影响痕感知和QOL的因素.
主要方法:
- 对67名接受过口腔机器人手术 (TORS) 和针对HPV+OPSCC的ND患者进行了回顾性病例对照研究.
- 利用修改的皮肤病生活质量指数 (mDLQI) 和自我意识量表 (SCS) 来评估痕感知和外观意识.
- 推迪的通用线性和逻辑回归模型分析了痕感知得分和患者/程序因素之间的关系.
主要成果:
- 平均mDLQI得分为0.84 (共30分),表明痕对QOL的影响普遍较低.
- 虽然私人保险和SCS得分显示了与mDLQI的一些关联,但它们不是临床上显著痕影响的重大风险因素.
- 大多数患者 (57%的应答率) 报告说,他们的部痕并没有显著干扰日常生活.
结论:
- 大多数为HPV+OPSCC接受ND的患者由于部痕而对他们的QOL产生最小的负面影响.
- 患者对部痕的看法相对一致,无论个体特征或治疗变化.
- 这项研究强调了HPV+OPSCC人群中部痕的一般积极心理调整.
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