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Updated: Jul 12, 2025

Efficient Production and Purification of Recombinant Murine Kindlin-3 from Insect Cells for Biophysical Studies
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一种新的白细胞粘附性缺陷III型突变表现出kindlin-3中紧的FERM域的功能重要性

Zhen Xu1, Shawn M Jobe2, Yan-Qing Ma3

  • 1Thrombosis and Hemostasis Program, Versiti Blood Research Institute, Milwaukee, Wisconsin, USA.

Journal of thrombosis and haemostasis : JTH
|October 22, 2023
PubMed
概括

一种新的突变破坏了kindlin-3s紧的FERM域的稳定,导致白细胞粘附性缺陷III (LAD-III). 这项研究证实了该域在整合素激活血液细胞功能的关键作用.

关键词:
血小板是血液中的血小板.遗传性疾病 (与生俱来的)血液静止 血液静止 血液静止血清细胞是白细胞.血小板缩症 血小板缩症

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