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Updated: Jul 12, 2025

Introducing a Gene Knockout Directly Into the Amastigote Stage of Trypanosoma cruzi Using the CRISPR/Cas9 System
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Introducing a Gene Knockout Directly Into the Amastigote Stage of Trypanosoma cruzi Using the CRISPR/Cas9 System

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对Trypanosoma cruzi amastigote转录组的分析揭示了具有复制和休眠寄生虫的异质种群

Hans Desale1, Claudia Herrera1, Eric Dumonteil1

  • 1Department of Tropical Medicine, School of Public Health and Tropical Medicine, and Vector-Borne and Infectious Disease Research Center, Tulane University, New Orleans, LA, USA.

Microbes and infection
|October 22, 2023
PubMed
概括

这项研究揭示了细胞内Trypanosoma cruzi amastigotes之间的异质性,确定了一个休眠的群体. 转录学有助于了解查加斯病中的寄生虫持久性.

关键词:
查加斯病是查加斯病的一种疾病.解体解体是一种解体.在休眠状态下.病原发生和发病的过程.在RNA-seqqq.复制复制复制复制复制复制复制

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Excavata is a diverse group of protists that includes both chemoorganotrophic and phototrophic species, with some thriving in anaerobic environments. Among the key groups within Excavata are diplomonads and parabasalids, which are flagellated protists that lack mitochondria and chloroplasts. These microorganisms typically inhabit anoxic environments, such as the intestines of animals, where they exist either symbiotically or as parasites, relying on fermentation for energy production. Some...
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