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Updated: Jul 12, 2025

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circ_SIRT1上调ATG12,通过与EIF4A3相互作用,促进CML中Imatinib的耐药性

Rong Zhang1, Jinjin Hao1, Hui Yu1

  • 1Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.

Gene
|October 22, 2023
PubMed
概括

一种新的循环RNA,circ_SIRT1,在耐伊马替尼布的慢性髓性白血病 (CML) 中被上调. 抑制circ_SIRT1可以通过向自和EIF4A3来克服耐药性,为CML患者提供新的治疗策略.

关键词:
在ATG12中,它是ATG12.在CML中,CML是CML.欧洲投资基金4A3A3对伊马替尼布产生抗药性在circ_SIRT1上

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