在COVID-19后持续症状的患病率和风险因素:系统性审查和元分析
De Luo1, Bingjie Mei2, Piao Wang1
1Department of General Surgery (Hepatopancreatobiliary Surgery), Affiliated Hospital of Southwest Medical University, Sichuan, China; Academician (Expert) Workstation of Sichuan Province, Metabolic Hepatobiliary and Pancreatic Diseases Key Laboratory of Luzhou City, Affiliated Hospital of Southwest Medical University, Sichuan, China.
概括
长期COVID的症状,如疲劳和焦虑是常见的,影响许多个人感染后. 风险因素包括严重的急性疾病,女性性别和年龄较大,这突显了持续患者支持的必要性.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 在COVID-19 (长期COVID) 之后持续的症状是一个重大的全球健康挑战.
- 了解与这些长期影响相关的患病率和风险因素至关重要.
研究的目的:
- 为了确定COVID-19感染后持续症状的患病率.
- 确定与这些长期症状发展相关的关键风险因素.
主要方法:
- 进行了一项全面的元分析,汇集了211项符合条件的研究的数据.
- 随机效应模型被用来分析超过1300万个人的患病率和风险比率.
- 研究质量使用乔安娜·布里格斯研究所和纽卡斯尔-太华尺度进行评估.
主要成果:
- 疲劳,呼吸障碍,PTSD,焦虑和抑郁是最常见的持续症状.
- 与非COVID-19患者相比,COVID-19患者的症状患病率明显高.
- 风险因素包括女性性别,年龄较大,严重急性疾病,并发病,住院时间较长和BMI较高.
结论:
- 这一元分析提供了关于长期COVID症状流行率和相关风险因素的强有力的概述.
- 这些发现强调了对COVID-19幸存者的持续监测和支持系统的必要性.
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