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化学抗原受体T细胞免疫治疗对T细胞恶性瘤的进展和陷

Mathew G Angelos1, Ruchi P Patel1, Marco Ruella1

  • 1Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

Transplantation and cellular therapy
|October 22, 2023
PubMed
概括

卡尔-T细胞疗法对B细胞癌症有希望,但在治疗T细胞恶性瘤方面面临挑战. 本综述探讨了T细胞衍生的瘤的障碍和进展.

关键词:
一种全基性CAR T细胞.编辑基础编辑化学抗原受体的化学抗原受体杀害兄弟的是一种罪行.周围T细胞淋巴瘤在T细胞急性淋巴细胞白血病.由于T细胞无形成.

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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