新生儿血液储存实践新生儿血液储存实践
Elizabeth P Crowe1, Ruchika Goel2, Nour Al-Mozain3
1Department of Pathology, Johns Hopkins University School of Medicine, 1800 Orleans Street, Sheikh Zayed Tower, Room 3081-A, Baltimore, MD 21287, USA.
Clinics in perinatology
|October 22, 2023
概括
新生儿血液储存缺乏正式指导,导致各种各样的做法. 血液成分的修改旨在提高面临输血风险的脆弱婴儿的安全性.
科学领域:
- 新生儿医学 新生儿医学
- 输血医学 输血医学
- 血液银行 血液银行
背景情况:
- 新生儿血液储存实践缺乏标准化的指导方针,导致机构的多样性.
- 新生儿是易受伤害的群体,有很高的输血负担,需要特别考虑血液产品.
- 现有的做法可能会对新生儿接受者产生意想不到的不良影响.
研究的目的:
- 审查当前的新生儿血液储存实践.
- 讨论新生儿血液产品修饰的潜在不良影响.
- 为了突出引发新生儿安全的血液成分修改变化的担忧.
主要方法:
- 关于新生儿血液储存实践的文献综述.
- 讨论血液产品选择标准 (新鲜度,储存介质,病原体不活化).
- 对新生儿接受者的潜在不良影响的分析.
主要成果:
- 新生儿血液储存实践存在广泛的机构差异.
- 血液产品的修改是由包括免疫缺陷,供体暴露和细胞巨乳病毒传播在内的担忧驱动的.
- 与当前的做法相关的潜在风险包括体积过载,高血和血液溶解.
结论:
- 需要为新生儿血液储存提供标准化指导.
- 仔细考虑血液产品的修改对于新生儿安全至关重要.
- 持续的研究和实践改进对于减轻新生儿输血相关风险至关重要.
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