在早产婴儿的异性带血输血
Luciana Teofili1, Patrizia Papacci2, Carmen Giannantonio3
1Transfusion Medicine Department, Fondazione Policlinico A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Largo Gemelli 8, Rome, Italy.
Clinics in perinatology
|October 22, 2023
概括
在早产儿重复输血可以降低胎儿的血红蛋白. 使用带血输血可以保护胎儿的血红蛋白,潜在地减少像早产视网膜病变这样的风险.
科学领域:
- 新生儿医学 新生儿医学
- 血液学 血液学 血液学
- 儿科生理学 儿科生理学
背景情况:
- 在早产新生儿中重复输血红细胞 (RBC),将胎儿血红蛋白 (HbF) 取代成年血红蛋白.
- 由于血红蛋白变化而增加的氧气输送可能导致细胞高氧化.
- 低HbF水平与早产的视网膜病变和支气管肺功能障碍症有关.
研究的目的:
- 审查使用全源带血输血背后的机制.
- 评估这种输血策略对早产新生儿的潜在益处.
- 用这种方法总结现有的临床经验.
主要方法:
- 审查有关红细胞输血,血红蛋白生理学和新生儿结果的现有文献.
- 对HbF保存的拟议机制的分析.
- 汇编了关于早产婴儿带血液输血的临床数据.
主要成果:
- 全基性带血输血可以增加血红蛋白水平,而不会显著耗尽HbF储备.
- 这一策略可以减轻与标准输血相关的细胞过氧的风险.
- 初步的临床数据表明可行性和潜在的益处.
结论:
- 给早产新生儿输血全源带血是一种保持HbF水平的有希望的策略.
- 这种方法可以减少输血相关疾病的发生率或严重程度,例如早产视网膜病变.
- 需要进一步的临床研究来证实疗效和优化方案.
相关概念视频
Bone Marrow Sampling and Transplants
341
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
341
Blood Transfusion and Agglutination
10.8K
Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
10.8K
Blood Transfusion
581
Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
581
Stem Cell Culture
5.2K
Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
5.2K


