转移性乳腺癌患者的性功能障碍
Nusrat Jahan1, Elizabeth Cathcart-Rake2, Robert A Vierkant3
1Division of Hematology and Oncology, University Alabama at Birmingham, Birmingham, AL.
Clinical breast cancer
|October 22, 2023
概括
性功能障碍在转移性乳腺癌 (MBC) 的女性中很常见. 阴道干燥是与增加性功能障碍严重程度相关的常见症状,需要临床评估和治疗讨论.
科学领域:
- 在瘤学瘤学.
- 性健康 性的健康
- 生活质量研究 研究 生命质量研究
背景情况:
- 性福利显著影响整体生活质量.
- 转移性乳腺癌 (MBC) 患者的性功能障碍仍然是一个研究不足的领域.
研究的目的:
- 调查新发MBC患者性功能障碍的患病率和严重程度.
- 为了确定与性功能障碍和特定症状 (如阴道干燥) 相关的因素.
- 在4年的时间里跟踪性功能障碍的变化.
主要方法:
- 利用了梅奥诊所乳腺疾病注册表 (MCBDR) 的数据.
- 包括被诊断为 de novo MBC 的患者,他们对性功能障碍调查做出了反应.
- 评估性功能障碍,在基线时使用0-10级,每年4年进行一次,并在2年和4年进行额外的症状特定问题.
主要成果:
- 在103名患者中,56.3%的患者在基线报告了性功能障碍,到4年增加到85%.
- 大约49% (2年) 和39% (4年) 的患者报告了阴道干燥.
- 阴道干燥与更高的性功能障碍严重程度显著相关.
结论:
- 自我报告的性功能障碍在新发MBC的女性中非常普遍.
- 阴道干燥是一种常见的,可治疗的症状,有助于性功能障碍的严重程度.
- 医疗保健提供者应该主动查MBC患者的性功能障碍,并提供治疗选择.
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