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Updated: Jul 12, 2025

Ex Vivo Analysis of Mechanically Activated Ca2+ Transients in Urothelial Cells
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阿克托米奥辛活性和皮埃佐1活性协同驱动泌尿系统纤维细胞激活

Guo Chen1,2, Xiaoshuai Gao1, Jiawei Chen1

  • 1Department of Urology, Institute of Urology (Laboratory of Reconstructive Urology), West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, P. R. China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|October 23, 2023
PubMed
概括

细胞机械力量,由肌二和皮埃佐1调节,驱动纤维化. 它们的相互作用创造了一个反循环,加剧了纤维细胞到肌纤维细胞的过渡,这表明Piezo1是膀纤维化治疗的治疗标.

关键词:
这是一个Piezo1.这种药物是actomyosin.纤维细胞的细胞.纤维化 纤维化泌尿系统 泌尿系统

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