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质瘤免疫治疗的全球研究趋势:全面的可视化和文献计量分析

Hong-Yu Zhang¹, Han-Yong Yu¹, Guo-Xu Zhao²

¹Department of Neurosurgery, Harbin Medical University, Harbin, China.

Frontiers in endocrinology

|October 23, 2023

概括

这项研究分析了2000年至2023年间质瘤免疫疗法研究趋势. 关键主题包括化学抗原受体T细胞 (CAR-T) 疗法和编程死亡-1 (PD-1) 抑制剂,突出显示未来的研究方向.

科学领域:

神经瘤学神经瘤学
免疫学免疫学免疫学
图书统计学图书统计学

背景情况:

质瘤是一种致命的脑癌,尽管目前的治疗方法,预后不佳.
免疫疗法为质瘤提供了一个有前途的治疗途径.
缺乏对研究趋势和质瘤免疫疗法热点的系统分析.

研究的目的:

阐明质瘤免疫疗法的全球研究趋势和知识结构.
通过图书统计分析,识别该领域的新兴热点和未来方向.

主要方法:

从Web of Science核心收藏中获取的2000-2023年间4910篇出版物的图书统计分析.
使用VOSviewer,CiteSpace,微软Charticulator和R的Bibliometrix包进行研究趋势的定量分析和可视化.

主要成果:

自2019年以来,年度出版物显示了上升趋势,美国是领先的国家.
关键的机构包括哈佛医学院,和著名的作者,如约翰·H·桑普森博士.
热门话题包括免疫疗法,质母细胞瘤和临床试验,新兴的重点是瘤微环境和CAR-T工程.

结论:

图书统计分析揭示了全球景观和质瘤免疫疗法的新兴趋势.
化学抗原受体T细胞 (CAR-T) 疗法,编程死亡-1 (PD-1) 和尼沃卢马布在当前的研究中占据着重要地位.
未来的研究应该探索特定的新抗原和预后标记,强调国际合作.

关键词:

在CART-T中,我们可以使用CAR-T.城市空间 (Citespace) 是一个城市空间.在VOSviewer中使用VOSviewer.圣经计量资料 (Bibliometric bibliometric bibliometric) 是指参考书目中的资料.质瘤质瘤是一种免疫疗法免疫疗法

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