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Updated: Jul 12, 2025

Analyzing and Building Nucleic Acid Structures with 3DNA
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Analyzing and Building Nucleic Acid Structures with 3DNA

Published on: April 26, 2013

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在 silico 中发现重复元素作为 3D 基因组折叠的关键序列决定因素

Laura M Gunsalus1,2, Michael J Keiser2,3,4,5,6, Katherine S Pollard1,3,7,8

  • 1Gladstone Institutes, San Francisco, CA, USA.

Cell genomics
|October 23, 2023
PubMed
概括

遗传变异可以改变DNA组织和基因活动. 深度学习方法显示,虽然大多数变化具有轻微影响,但特定的DNA序列显著影响染色质相互作用,为3D基因组调节提供了洞察力.

关键词:
三维基因组是3D的基因组.在CTCF中,CTCF是指CTCF.在这种情况下,染色染色素机器学习是机器学习.重复的元素是重复的元素.

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