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Updated: Jul 12, 2025

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跨种群的多基因预测受到祖先,遗传架构和方法论的影响

Ying Wang1,2, Masahiro Kanai1,2,3,4, Taotao Tan5

  • 1Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA 02114, USA.

Cell genomics
|October 23, 2023
PubMed
概括

多祖先多基因风险评分 (PRS) 在多种不同的人群中通常优于单祖先PRS. 整合本地祖先数据可以提高PRS在非洲祖先的表现.

关键词:
遗传架构 遗传建筑 遗传架构全基因组关联研究研究.多个祖先的多个祖先.多基因风险得分的多基因风险得分.

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