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Updated: Jul 12, 2025

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
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Published on: June 15, 2011

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系统地调查精神分裂症相关常见变异的等位基调调节活性

Jessica C McAfee1,2,3, Sool Lee1,2,4, Jiseok Lee1,2

  • 1Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

Cell genomics
|October 23, 2023
PubMed
概括

研究人员使用大规模并行报告测试 (MPRA) 识别了与精神分裂症风险相关的439种遗传变异. 这种方法揭示了其他方法遗漏的调节变异,为疾病提供了新的见解.

关键词:
在GWAS中,GWAS就是GWAS.在MPRA中,MPRA是MPRA.接触式可访问性模型染色体的架构 染色体的架构我们的eQTL是eQTL.基因调节 基因调节 基因调节高通量记者检测测试验没有编码的变体.精神分裂症是一种精神分裂症.变量函数的变量函数是一个变量函数.

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