帕拉克瓦特诱导的急性脏和肺损伤与甲基前尼索隆的剧烈反应:一个案例报告
相关实验视频
Updated: Jul 12, 2025
06:52
Induction of Mouse Lung Injury by Endotracheal Injection of Bleomycin
Published on: April 30, 2019
17.5K
Md Asaduzzaman1, Soumitra Roy2, Nibedita Das Pew3
1Department of Medicine, Sylhet MAG Osmani Medical College Hospital, Sylhet 3100, Bangladesh.
Toxicology reports
|October 23, 2023
概括
帕拉克瓦特中毒是全球重要的健康问题. 早期使用免疫抑制药物甲基普雷迪尼索隆 (methylprednisolone) 治疗,有望改善帕拉克瓦特中毒患者的生存率.
科学领域:
- 毒理学 毒理学 毒理学
- 药理学 药理学是指药理学的学科.
- 内部医学 内部医学
背景情况:
- 帕奎特中毒是全球致命中毒的主要原因之一,特别是在农业地区.
- 高毒性导致通过自由基损伤快速,多器官损伤 (脏,肺,肝脏).
- 没有特定的解毒剂存在,使得早期诊断和支持性护理至关重要.
相关概念视频
01:26Anticholinesterase Agents: Poisoning and Treatment
889
Anticholinesterases, also known as cholinesterase inhibitors, work by blocking the breakdown of acetylcholine, leading to its accumulation in the synaptic cleft. This accumulation indirectly enhances both muscarinic and nicotinic actions. These agents are classified as reversible or irreversible based on their mechanism of action.
Irreversible agents form a strong bond with the cholinesterase enzyme, making it inactive. The breakdown of the phosphorylated enzyme is...
Irreversible agents form a strong bond with the cholinesterase enzyme, making it inactive. The breakdown of the phosphorylated enzyme is...
889
01:29Acute Respiratory Failure-V
143
The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Ensure that patients are monitored continuously for their response to therapy, including changes in...
143