胃肠穿孔的危险因素与预后不佳的胃肠穿孔
Wenqing Yuan1, Xiaozhuan Zhou2, Zhigao Cai1
1Department of Gastrointestinal Surgery, Longchuan County People's Hospital, Heyuan, 517300, People's Republic of China.
International journal of general medicine
|October 23, 2023
概括
确定胃肠道穿孔的危险因素对于改善患者的治疗结果至关重要. 这项研究强调了关键指标,如穿孔部位,营养标志物和与不良预后和死亡率相关的炎症比率.
科学领域:
- 胃肠病学和外科手术
- 临床病理学 临床病理学
- 医学研究 医学研究
背景情况:
- 胃肠道穿孔仍然是死亡的重要原因,尽管医学的进步.
- 确定预后因素对于管理胃肠道穿孔患者至关重要.
研究的目的:
- 确定与胃肠道穿孔患者预后不佳相关的危险因素.
- 分析胃肠道穿孔患者的实验室数据和临床结果.
主要方法:
- 在2019年1月至2022年2月期间诊断出胃肠道穿孔的240名患者的回顾性分析.
- 使用单变量和多变量分析来确定风险因素.
- 根据住院时间,败血症休克和死亡率对患者进行分组.
主要成果:
- 下消化道穿孔,低总蛋白和低血红蛋白与更长的住院时间有关.
- 高的中性粒细胞与淋巴细胞比率 (NLR),高的淋巴细胞与单细胞比率 (LMR) 和低的预后营养指数 (PNI) 预测了性休克.
- 高NLR,高LMR和低PNI被确定为死亡风险因素,特定的标记物如白蛋白和PNI显示出基于穿孔部位的意义.
结论:
- 穿孔部位,总蛋白质,白蛋白,血红蛋白,NLR,LMR,PLR和PNI是胃肠穿孔的重要危险因素,预后不佳.
- 这些确定的因素可以帮助胃肠道穿孔患者的风险分层和临床决策.
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