在Ross程序之后,对事件发生的时间和长期结果进行系统审查和元分析
Junichi Shimamura1, Shinichi Fukuhara2, Yujiro Yokoyama3
1Division of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, GA, USA.
Journal of thoracic disease
|October 23, 2023
概括
罗斯手术为成年人提供了很好的生存率,在20年内,大约20%的患者需要重新干预. 这项研究分析了罗斯手术的长期结果,这是一种关键的大动脉替代品.
科学领域:
- 心血管外科心血管外科
- 胸部外科手术 胸部外科手术
- 心脏门手术 心脏门手术
背景情况:
- 对非老年人的最佳主动脉替代品进行了辩论.
- 罗斯程序已经产生了大量的长期结果数据.
- 本研究的重点是从现有文献中分析这些结果.
研究的目的:
- 为了对罗斯程序的时间到事件结果进行元分析.
- 评估长期生存率和重新干预率.
- 评估罗斯手术作为大动脉置换术的有效性.
主要方法:
- 在主要数据库 (MEDLINE,EMBASE,Cochrane,Web of Science,Google Scholar) 进行了全面的文献搜索,截至2022年6月.
- 包括的研究报告了罗斯手术超过20年的临床结果.
- 分析的重点是晚期的生存和无需自体移植或右心室外流通道 (RVOT) 重新干预.
主要成果:
- 对包括4910名患者在内的6项研究的分析显示了高生存率:87.4%±1.9%在20年后.
- 20年后从自体移植重新干预中获得的自由率为84.8%±2.5%.
- 20年后,没有任何门再干预 (自体移植或RVOT) 的情况为80.8%±2.5%.
结论:
- 罗斯手术证明了出色的长期存活率.
- 大约20%的患者可能需要自移植或RVOT重新干预20年.
- 这些发现支持罗斯手术作为大动脉替代品的可行性.
相关概念视频
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