Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

REM Sleep Behavior Disorder01:15

REM Sleep Behavior Disorder

211
REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
211
Sleep-Wake Cycles01:24

Sleep-Wake Cycles

1.4K
Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and  rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
1.4K
Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

174
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
174
Nightmares and Night Terrors01:18

Nightmares and Night Terrors

95
Nightmares and night terrors represent two distinct types of sleep disturbances that differ in timing, characteristics, and the sleeper's recall of the event. Nightmares are vivid, disturbing dreams that usually awaken the sleeper from REM sleep, a stage of sleep where brain activity is high, and dreams are most frequent. Upon awakening, individuals often have detailed recollections of their nightmares, which can include themes of threats to survival, security, or self-esteem.
Nightmares...
95
Narcolepsy01:07

Narcolepsy

119
Narcolepsy is a chronic sleep disorder characterized by pervasive, uncontrolled sleepiness and other sleep disturbances. One of its hallmark symptoms is an abrupt transition to REM sleep upon falling asleep, which causes symptoms typically associated with this phase to occur unexpectedly during wakefulness. These include the following symptoms, which typically last from a minute or two to half an hour.
119
Sedatives and Hypnotics Drugs: Miscellaneous Agents01:17

Sedatives and Hypnotics Drugs: Miscellaneous Agents

183
Sedatives and hypnotics encompass a wide range of substances, each with its unique mechanism of action, uses, and potential adverse effects.
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
183

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

The Prodromal Synucleinopathy Rating Scale: An Assessment in Patients With REM Sleep Behavior Disorder.

Neurology·2026
Same author

Characterization of patients with isolated REM sleep behavior disorder and cerebrospinal fluid α-synuclein negativity.

NPJ Parkinson's disease·2026
Same author

Prognostic Determinants of Presentation and Outcome in Anti-IgLON5 Disease.

Neurology(R) neuroimmunology & neuroinflammation·2026
Same author

Clinical markers of disease progression in the prodromal to overt alpha-synucleinopathy continuum.

Brain : a journal of neurology·2026
Same author

Genetic associations between post-traumatic stress disorder and REM-sleep behavior disorder.

NPJ Parkinson's disease·2026
Same author

Identification and Enrollment of Individuals Prior to Parkinson's Disease Diagnosis: Biomarker-Driven Adaptive Eligibility and Enrollment into the Parkinson's Progression Markers Initiative.

Annals of neurology·2026

相关实验视频

Updated: Jul 12, 2025

Author Spotlight: Overcoming Challenges in Drosophila Sleep Measurement Using DAM System
05:59

Author Spotlight: Overcoming Challenges in Drosophila Sleep Measurement Using DAM System

Published on: October 20, 2023

2.4K

快速睡眠行为障碍正在变化吗? 世俗变化与参考模式对比

Stephen Joza1, Alex Iranzo2, Ambra Stefani3

  • 1Montreal Neurological Institute McGill University Montreal Quebec Canada.

Movement disorders clinical practice
|October 23, 2023
PubMed
概括
此摘要是机器生成的。

增加公众对孤立快速眼动 (REM) 睡眠行为障碍 (iRBD) 的认识,导致更早的临床表现. 这导致更长的时间来phenoconversion,改善患者的无病生存率.

关键词:
帕金森病的疾病.雷姆睡眠行为障碍 雷姆睡眠行为障碍患有利维体痴呆症的痴呆症患病率的流行情况.世俗的趋势是世俗的.

更多相关视频

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice
10:56

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice

Published on: August 2, 2017

10.1K
Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
04:33

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression

Published on: April 26, 2024

716

相关实验视频

Last Updated: Jul 12, 2025

Author Spotlight: Overcoming Challenges in Drosophila Sleep Measurement Using DAM System
05:59

Author Spotlight: Overcoming Challenges in Drosophila Sleep Measurement Using DAM System

Published on: October 20, 2023

2.4K
Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice
10:56

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice

Published on: August 2, 2017

10.1K
Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
04:33

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression

Published on: April 26, 2024

716

科学领域:

  • 神经学 神经学
  • 睡眠医学 睡眠医学
  • 公共卫生 公共卫生

背景情况:

  • 自2014年以来,对孤立/异常性快速眼动 (REM) 睡眠行为障碍 (iRBD) 的公众宣传增加了,特别是在蒙特利尔.
  • 研究提高认识对疾病进展和呈现时间的影响.

研究的目的:

  • 为了确定较轻微的iRBD病例是否随着时间的推移呈现较早.
  • 为了比较在不同时间段和转诊类型中招募的iRBD患者队列之间的无疾病生存率.

主要方法:

  • 来自三个主要中心的iRBD患者数据的回顾性分析,比较两个招聘时期 (2004-2013年和2014-2022年).
  • 基于转诊类型 (自我转诊与常规转诊) 的无疾病生存率和变现时间的比较.

主要成果:

  • 在蒙特利尔,在2014年之前诊断的患者显示,与晚期诊断 (23%在5年后) 相比,转变的时间 (42%在5年后) 显著缩短.
  • 在巴塞罗那和因斯布鲁克的队列中没有观察到表态转换的显著差异.
  • 在蒙特利尔,晚期的生存率增加与更多的自我转诊患者有关,与医生转诊的患者相比,自我转诊患者的变现率降低了3倍.

结论:

  • 提高患者对iRBD的认识,有助于更早地向医疗保健专业人员介绍iRBD.
  • 早期的临床关注,由公众推广驱动,与更长的时间进行表态转化和改善无疾病生存相相关.