胃肠功能障碍在的人综合征频谱障碍中的许多面孔
Jacqueline Koshorek1, Yujie Wang1,2, Daniela Pimentel Maldonado1
1Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Frontiers in neurology
|October 23, 2023
概括
胃肠道 (GI) 症状在的人综合征谱系障碍 (SPSD) 中很常见. 一项研究发现,32%的SPSD患者经历了胃肠道问题,许多患者表现出运动异常,这表明需要进行胃肠道查.
科学领域:
- 神经学 神经学
- 胃肠病学 胃肠病学
背景情况:
- 刚性人群综合征谱系障碍 (SPSD) 是一种自身免疫性疾病,其胃肠道 (GI) 影响尚不清楚.
- 在SPSD中表征肠道功能障碍对于患者管理至关重要.
研究的目的:
- 为了确定患有SPSD的个体中肠道功能障碍的患病率和类型.
- 为了识别与SPSD相关的常见的胃肠道症状和不运动模式.
主要方法:
- 对240名SPSD患者的回顾性图表审查.
- 评估胃肠道症状,SPSD表型和胃肠道运动测试结果.
- 使用了描述性统计和千平方分析.
主要成果:
- 32%的SPSD患者报告了胃肠道症状,最常见的是消化不良,便秘和恶心/吐.
- 在接受测试的患者中,44.4%的患者患有上部消化道不运动,17%的患者患有下部消化道不运动,4%患有扩散性消化道不运动.
- 没有消化道运动测试的患者中,更高比例的患者患有糖尿病.
结论:
- 胃肠道症状和过渡异常在SPSD患者中很普遍.
- 考虑在出现胃肠道症状的SPSD患者中进行胃肠道运动测试.
- 需要进行进一步的纵向研究,以了解SPSD患者的预后和治疗.
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