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无创性左心室压力-应变心肌动脉工作在功能良好的双主动脉和主动脉扩张的患者:一项初步研究

Yuting Tan^1,2,3, Yuman Li^1,2,3, Jiawei Shi^1,2,3

¹Department of Ultrasound, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Quantitative imaging in medicine and surgery

|October 23, 2023

概括

心肌工作 (MW) 有效地评估双管主动脉患者的早期心脏功能变化. 与全球纵向应变 (GLS) 不同,MW可以区分大动脉扩张对左心室功能的负面影响.

科学领域:

心脏病学心脏病学
生物医学工程生物医学工程
医疗成像医学成像

背景情况:

双动脉 (BAV) 是一种常见的先天性心脏缺陷.
左心室 (LV) 功能评估对于管理BAV患者至关重要.
需要新的非侵入性方法来评估BAV中的LV功能.

研究的目的:

在具有良好功能BAV的患者中分析心肌工作 (MW).
探索大动脉扩张和动脉硬性对BAV患者LV功能的影响.
为了比较MW和全球纵向应变 (GLS) 在检测早期心肌功能障碍方面的疗效.

主要方法:

招募了104名BAV患者和50名对照人群.
测量包括全球工作指数 (GWI),全球建设性工作 (GCW),全球浪费工作 (GWW),全球工作效率 (GWE),GLS和大动脉硬度指数.
根据上升的大动脉直径,BAV患者被分为以下子组:非扩张,轻度扩张和中度扩张.

主要成果:

与对照组相比,BAV患者的GWI,GCW,GWW和大动脉硬度增加,GWE和GLS降低.
在BAV患者中,轻度和中度扩张的大动脉与增加的GWW和大动脉硬度相关,并减少了GWE.
大动脉硬度指数独立地影响了所有MW参数 (GWI,GCW,GWW,GWE).

结论:

心肌工作 (MW) 可以在BAV患者中检测出早期心肌功能障碍.
在区分大动脉扩张对LV功能的有害影响方面,MW优于GLS.
动脉硬是影响BAV患者LV功能的一个关键因素.

关键词:

心肌工作 (MW)大动脉扩张的扩张.大动脉硬度指数指数双主动脉 (BAV) 两主动脉

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