对于只有MRI可疑的乳腺病变的定量明显扩散系数指标:任何临床附加值吗?
Xue Li1,2, Hong Wang1,2, Jiayin Gao1,2
1Department of Radiology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.
Quantitative imaging in medicine and surgery
|October 23, 2023
概括
从扩散权重成像 (DWI) 获得的定量显微扩散系数 (ADC) 度量有效评估MRI-only乳腺病变. 平均ADC值在区分良性和恶性MRI病变方面显示出最高的诊断性能.
科学领域:
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
- 医疗成像医学成像
背景情况:
- 仅通过MRI检测到的可疑乳腺病变 (仅MRI病变) 存在诊断挑战,因为它们的尺寸很小,表征不佳.
- 评估这些只有MRI的病变需要先进的成像技术来准确诊断和管理.
研究的目的:
- 调查从扩散权重成像 (DWI) 获得的定量显微扩散系数 (ADC) 度量的临床意义.
- 评估ADC指标的诊断性能,以区分良性与恶性MRI-only乳腺病变.
主要方法:
- 分析了90个可疑的MRI病变 (51个恶性,39个良性).
- 计算了BI-RADS的形态和运动参数和ADC指标 (ADCmin,ADCmax,ADC平均值,ADC异质性).
- 用接收器操作特征 (ROC) 曲线分析来评估诊断性能.
主要成果:
- 与BI-RADS参数相比,定量ADC指标显示出更高的诊断性能.
- 平均ADC (ADC平均值) 显示了最高的诊断性能 (AUC=0.825对于群体,0.812对于非群体).
- ADCmean和ADCmax对于仅MRI质量具有价值,而大小,分布,ADCmin和ADCmean对于非质量病变具有意义.
结论:
- 定量ADC指标对于区分只有MRI的乳腺病变是有价值的.
- 平均ADC (ADC平均值) 是区分良性和恶性MRI病变的最佳参数.
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