患有COVID-19的重症患者的细菌血流感染:一个回顾性队列研究
Mateusz Bartoszewicz1, Sławomir Lech Czaban2, Klaudia Bartoszewicz3
1Department of Anaesthesiology and Intensive Care, Medical University of Bialystok, Malmeda, Bialystok, Podlaskie, 15-089, Poland.
Therapeutic advances in infectious disease
|October 23, 2023
概括
危急的COVID-19患者有高血流感染 (BSI) 的风险. 关键的风险因素包括长时间的机械通风和ICU停留,多抗药性病原体是常见的.
科学领域:
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
- 流行病学 流行病学
背景情况:
- 患有2019年新冠肺炎 (COVID-19) 的重症监护病房 (ICU) 的患者面临患有血流感染 (BSI) 的重大风险.
- 了解与BSI相关的特定特征和风险因素在这个脆弱人群中对于有效管理至关重要.
研究的目的:
- 为了确定导致BSI的流行病原体,在重症COVID-19患者中.
- 确定与这种患者群体中BSI发生相关的因素.
主要方法:
- 进行了一项回顾性队列研究,涉及201名COVID-19的ICU患者.
- 用物流回归分析来确定BSI的风险因素,并对临床特征和结果进行分析.
主要成果:
- 血液感染 (BSI) 在21.4%的患者中发生,与没有BSI的患者相比,死亡率不显著.
- 严重的BSI风险因素包括机械通风的持续时间,与呼吸机相关的肺炎,ICU停留时间,高体重指数和男性性别.
- 主要致病原体是Klebsiella pneumoniae,Acinetobacter baumannii和Enterococcus faecalis,其中87%的BSI是由多药耐药生物体引起的.
结论:
- 在COVID-19患者中识别常见的病原体和BSI风险因素对于及时干预和预防策略至关重要.
- 长时间的机械通风和ICU停留时间成为显著的风险因素,突出了重症监护机构感染控制措施的重要性.
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