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传统与水下内切除对于表面非膜十二指甲状腺上皮瘤的传统与水下内切除

Hajime Miyazaki¹, Osamu Dohi¹, Tsugitaka Ishida^1,2

¹Molecular Gastroenterology and Hepatology, Graduate School of Medical Sciences, Kyoto Prefectural University of Medicine, Kyoto, Japan.

Japanese journal of clinical oncology

|October 23, 2023

概括

与传统的内镜粘膜切除 (CEMR) 相比,水下内镜粘膜切除 (UEMR) 对表面非膜十二指甲上皮瘤提供更高的R0切除率. 对于较小的病变,UEMR显示有前途,尽管存在学习曲线.

科学领域:

胃肠病学胃肠病学
内視鏡外科手術內視鏡外科手術
在瘤学瘤学.

背景情况:

表面非腹膜十二指甲上皮瘤 (SNADETs) 越来越多地通过内镜切除进行管理.
传统的内镜粘膜切除 (CEMR) 和水下内镜粘膜切除 (UEMR) 是不那么侵入性的治疗选择.

研究的目的:

为了比较CEMR和UEMR对SNADETs的结果.
在这两种技术中评估切除深度和肌肉粘膜的参与.

主要方法:

单中心回顾性队列研究 (2009年1月至2021年12月).
对 SNADET 进行 CEMR 与 UEMR 的患者的倾向性得分匹配.
对临床病理学结果的分析.

主要成果:

超低电磁共振实现了显著更高的R0切除率 (70.3%),而不是CEMR (50.0%).
与不完全切除 (RX/R1) 相关的因素包括较大的病变大小 (>10毫米) 和CEMR.
两种方法之间没有观察到切除深度或肌肉粘膜制的显著差异.

结论:

对于≤10毫米的SNADET,UEMR可能优于CEMR.
UEMR可能有一个的学习曲线.
需要进一步的大型多中心前性研究来验证UEMR的有效性.

关键词:

进行内镜粘膜切除.倾向性得分匹配的比分匹配切割的深度切割的深度.表面非皮十二指甲上皮瘤在水下进行内镜粘膜切除.

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