在儿童中,用于中耳炎与输液 (OME) 的腺切除术
Samuel MacKeith1, Caroline A Mulvaney2, Kevin Galbraith2
1ENT Department, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
The Cochrane database of systematic reviews
|October 23, 2023
概括
腺切除术可能会略微减少儿童持续性中耳炎与输液 (OME),但关于听力改善的证据尚不确定. 出血的风险很小,但需要更多的研究来确定哪些儿童从这种干预中获益最多.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 儿科手术 儿科手术
- 基于证据的医学基于证据的医学.
背景情况:
- 中耳炎与溢出 (OME) 是一种常见的儿童疾病,导致中耳液,可能导致听力损失和发育问题.
- 对OME的管理选择包括警等待,自膨胀和外科干预,如腺切除术,通常使用通风管.
研究的目的:
- 评价腺切除术的益处和危害,有或没有通风管,用于治疗儿童的OME.
- 综合来自随机和准随机受控试验的证据,将腺切除术与非手术或没有治疗进行比较.
主要方法:
- 随机对照试验和准随机试验的系统审查和元分析.
- 包括6个月至12岁的儿童,患有单边或双边OME.
- 主要结局包括听力,中耳炎特定的生活质量和出血;次要结局包括OME持久性,不良影响和发展里程碑.
主要成果:
- 对腺切除术对听力恢复的影响的证据在比较中非常不确定.
- 腺切除术可能会略微减少OME的持续性,但临床意义很小,证据的确定性非常低.
- 手术后出血的风险似乎很小,尽管对一些比较的证据有限且不确定.
结论:
- 关于儿童OME腺切除术的总体证据确定性低至非常低.
- 虽然腺切除术可能会降低OME的持续性,但它对听力的影响需要进一步调查.
- 未来的研究应该专注于确定特定的患者亚组,这些患者最有可能从腺切除术中受益.
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