老年患者喉喉逆流的时间点分布特征
Zhi Liu1,2, Chun Zhang1, Lianlian Liu1
1Department of Otolaryngology, The Sixth Medical Center of PLA General Hospital of Beijing, Beijing, China.
概括
年轻的喉回流 (LPR) 患者在饭后经历更多的下喉近道回流发作 (HREs). 老年LPR患者没有显著的餐时间HREs变化,但夜间HREs更多.
科学领域:
- 胃肠病学 胃肠病学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 老年病的医生 老年病的医生
背景情况:
- 喉回流 (LPR) 影响所有年龄段的人,但其表现和时间可能因年龄组而异.
- 了解下-近道逆流发作 (HREs) 的时间模式对于有效的LPR管理至关重要.
研究的目的:
- 调查老年和年轻患者诊断出LPR的HREs的时间点分布.
- 为了比较这两个年龄组之间的HREs相对于餐时间的发生模式.
主要方法:
- 进行了一项回顾性队列研究,涉及305名LPR症状患者.
- 患者接受了24小时的下-食道多通道内阻抗-pH (HEMII-pH) 监测.
- 通过将患者分成两组来分析数据:老年人 (>60岁) 和年轻人 (≤60岁).
主要成果:
- 在年轻患者中,HREs (不包括非酸气类型) 在饭后2小时内增加,特别是在晚餐后.
- 在老年人群中,在饭前和饭后的HRE发病率中没有发现显著差异.
- 与年轻患者相比,老年患者的夜间HREs发生率在统计上更高,特别是酸/无酸液体HREs.
结论:
- 较年轻的LPR患者在餐后增加HREs,根据反流类型的变化.
- 老年LPR患者在餐前或餐后没有显著的HRE变化,但更容易发生夜间液体HREs.
- 这些与年龄相关的HRE时间差异对于理解LPR病理生理学和指导治疗策略至关重要.
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