通过[18F]胆正电子发射断层扫描/计算机断层扫描偶然检测到类肺癌
Rensi Marco1, Decio Capobianco1, Di Gregorio Fernando1
1Azienda Sanitaria Universitaria Integrata, Nuclear Medicine Unit, Udine, Italy.
Molecular imaging and radionuclide therapy
|October 23, 2023
概括
这一案例凸显出,即使前列腺癌进展,高[18F]胆吸收的肺结节可能表明二次癌症. 在这种情况下,组织病理学评估对于准确诊断至关重要.
科学领域:
- 在瘤学瘤学.
- 核医学就是核医学.
- 辐射疗法 辐射疗法
背景情况:
- 前列腺癌 (PCa) 管理包括激素治疗和放射治疗 (RT).
- 尽管初始治疗,PCa的骨进展可能会发生.
- [18F] - 胆正子发射断层扫描/计算机断层扫描 (PET/CT) 用于检测复发.
研究的目的:
- 由于[18F]-胆PET/CT的意外发现,报告一个错误诊断的案例.
- 强调对具有高辐射追踪器吸收率的肺结节进行基因病理学确认的重要性.
主要方法:
- 一名79岁的男性有PCa病史,接受了[18F]胆PET/CT,以检查生化复发.
- 在PET/CT上鉴定出可疑的肺结节上进行了CT导向活检.
主要成果:
- 患者呈现了PCa的骨进展和肺结节.
- [18F]胆PET/CT在骨病变和肺结节中显示出显著的吸收.
- 活检证实肺结节是一种类肺癌,而不是转移性PCa.
结论:
- 在PCa患者的肺结节中显著的[18F]胆吸收可以代表单独的原发性恶性瘤.
- 对于具有高放射性标记胆吸收率的肺结节的最终诊断,组织病理学评估是强制性的.
- 这一案例强调了在瘤成像中需要谨慎差异诊断的必要性.
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