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Updated: Jul 12, 2025

Generation of RNA/DNA Hybrids in Genomic DNA by Transformation using RNA-containing Oligonucleotides
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Generation of RNA/DNA Hybrids in Genomic DNA by Transformation using RNA-containing Oligonucleotides

Published on: November 24, 2010

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对TREX1的特定酶性质的分子洞察力,揭示了在处理RNA和DNA/RNA杂交物中的多种功能

Kuan-Wei Huang1,2, Chia-Yun Wu1,2, Shu-Ing Toh1,2

  • 1Department of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu 30068, Taiwan.

Nucleic acids research
|October 23, 2023
PubMed
概括

功能障碍的三位数修复外核酶1 (TREX1) 导致自身免疫性疾病. 这项研究揭示了TREX1可以消化单链RNA和DNA/RNA混合体,但不能消化双链RNA,从而提供了对其外核酶活性的见解.

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