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Updated: Jul 12, 2025

Identification of Inositol Phosphate or Phosphoinositide Interacting Proteins by Affinity Chromatography Coupled to Western Blot or Mass Spectrometry
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Identification of Inositol Phosphate or Phosphoinositide Interacting Proteins by Affinity Chromatography Coupled to Western Blot or Mass Spectrometry

Published on: July 26, 2019

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伊诺西六酸盐刺激NHEJ的结构和功能基础通过稳定Ku-XLF相互作用来稳定NHEJ

Antonia Kefala Stavridi1, Amandine Gontier2, Vincent Morin2

  • 1Heartand Lung Research Institute, University of Cambridge, Biomedical Campus, Papworth Road, Trumpington, Cambridge CB2 0BB, UK.

Nucleic acids research
|October 23, 2023
PubMed
概括

代谢物伊诺西-六酸盐 (IP6) 通过与Ku70-Ku80异构体 (Ku) 结合来增强DNA修复,使其稳定在DNA上,并促进非同类末端结合 (NHEJ) 途径.

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