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在全国代表性样本中使用第二代抗糖尿病药物
Bang Truong, Yuexin Li, Jingyi Zheng
1Department of Health Outcomes Research and Policy, Auburn University Harrison College of Pharmacy, 4306d Walker Building, Auburn, AL 36849.
The American journal of managed care
|October 23, 2023
概括
在美国,14%的2型糖尿病患者使用了第二代抗糖尿病药物. 更高的收入,更多的药物使用和升高的血红蛋白A1c水平与他们的处方有关.
科学领域:
- 内分泌学 在内分泌学.
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
背景情况:
- 第二代抗糖尿病药物为2型糖尿病 (T2D) 管理提供了好处.
- 这些药物的实际使用模式仍然不完全理解.
- 评估影响患者采用这些药物的因素对于优化T2D护理至关重要.
研究的目的:
- 调查与使用第二代抗糖尿病药物相关的患者特征.
- 分析真实世界的数据,以代表性美国人群的T2D吸收新的抗糖尿病疗法.
主要方法:
- 对2005-2018年国家健康和营养检查调查 (NHANES) 数据的回顾性,横截面分析.
- 纳入标准:成年人 (≥18岁) 确诊T2D使用抗糖尿病药物30天内.
- 权衡的多变量逻辑回归模型评估了患者因素与第二代抗糖尿病药物使用之间的关联.
主要成果:
- 在4493名T2D患者中,大约13.67%的人报告使用至少一种第二代抗糖尿病药物.
- 较高的收入 (≥400%联邦贫困水平),增加的药物负担和更高的血红蛋白A1c水平与使用这些药物有显著的关联.
- 调整后的几率比率表明,具有这些特征的患者使用的可能性更高.
结论:
- 在美国2型糖尿病患者中,第二代抗糖尿病药物的使用率约为14%.
- 诸如更高的社会经济地位和更严重的疾病严重程度等因素似乎影响了这些新药的处方.
- 政策干预措施,如优化处方福利设计以减少自付费用,可以提高患者获取和改善临床结果.
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