社会经济因素与2型糖尿病患者药物不良服药相关
Marie Ekenberg1, Miriam Qvarnström2, Anders Sundström2
1Department of Pharmacy, Faculty of Pharmacy, Uppsala University, Uppsala, Sweden. marie.ekenberg@farmaci.uu.se.
European journal of clinical pharmacology
|October 23, 2023
概括
社会经济因素对2型糖尿病患者的药物开始和持续有重大影响. 了解这些差异是改善治疗坚持治疗的关键.
科学领域:
- 临床药房 临床药房
- 公共卫生 公共卫生
- 糖尿病管理 糖尿病管理
背景情况:
- 2型糖尿病需要长期的药物管理.
- 药物坚持,包括开始和持续,对于有效的2型糖尿病治疗至关重要.
- 社会经济因素可能会影响对抗糖尿病药物的坚持.
研究的目的:
- 研究2型糖尿病患者首次服用抗糖尿病药物的发病率和持续率.
- 检查社会经济因素与药物开始和持续使用之间的关联.
主要方法:
- 在瑞典乌普萨拉 (Uppsala) 的8515名2型糖尿病患者 (2012-2019) 的队列研究.
- 使用药物索赔数据和国家社会经济登记册来评估开始 (30天内) 和持续 (24个月).
- 多变量逻辑回归分析了与年龄,性别,生活状况,出生国,教育,职业和收入的关联.
主要成果:
- 92.4%的患者在30天内开始第一次服用抗糖尿病药物;64.0%的患者在24个月后持续服用.
- 失业与较低的启动率有关;女性性别与较低的持久性有关.
- 低收入,极端年龄,非欧洲出生和非甲福林处方与低发病率和持续性有关.
结论:
- 社会经济因素对2型糖尿病的药物开始和持续有不同的影响.
- 认识到这些差异对于制定针对性的干预措施来打击药物不服药是必不可少的.
- 需要量身定制的策略来改善不同患者群体的长期治疗坚持.
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