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G9a和Sirtuin6在表观遗传上调节宿主胆固醇的积累,以促进菌根细菌的生存

Praveen Prakhar1, Bharat Bhatt1, Gaurav Kumar Lohia1

  • 1Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, Karnataka, India.

PLoS pathogens
|October 23, 2023
PubMed
概括

主体胆固醇的积累有助于Mycobacterium结核病 (Mtb) 通过减少氧化压力生存. 基斯基因修饰剂G9a和SIRT6协调了这一过程,为Mtb感染提供了新的治疗点.

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