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Updated: Jul 12, 2025

A RANKL-based Osteoclast Culture Assay of Mouse Bone Marrow to Investigate the Role of mTORC1 in Osteoclast Formation
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AMPKα1负面调节骨质结晶发生并减轻病态骨质损失

Mariana S P Ribeiro1, Lucas G R Venturini1, Cesar A Speck-Hernandez1

  • 1Laboratory of Bone Biology, Department of BioMolecular Sciences, School of Pharmaceutical Sciences Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil.

The Journal of biological chemistry
|October 23, 2023
PubMed
概括

由AMP激活的蛋白激酶α1 (AMPKα1) 负面调节骨质细胞的形成和功能. 它在骨质细胞中的耗尽加速了骨质流失,这表明AMPKα1是骨质疏松症等骨解病的治疗点.

关键词:
这就是AMPKK.代谢 代谢 代谢 代谢骨质结晶体的骨质细胞.骨质细胞生成 (osteoclastogenesis) 是一个过程.骨质疏松症是一种骨质疏松症.

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