活性麻醉剂的使用和口腔后内镜肌瘤结局在食道运动障碍中的结果
Pei Xue1, Andrew Canakis2, David Uihwan Lee2
1Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Gastrointestinal endoscopy
|October 23, 2023
概括
活性麻醉剂的使用对食道运动障碍的口腔内镜肌切除术 (POEM) 后的症状改善产生负面影响. 服用麻醉药物的患者在术后得分更高,这表明治疗结果不那么成功.
科学领域:
- 胃肠病学 胃肠病学
- 最少侵入性的手术
- 药理学 药理学是指药理学的学科.
背景情况:
- 消化管运动障碍的治疗方法是口腔内镜肌切除术 (POEM).
- 阿片类药物的使用与食道动力障碍有关.
- 麻醉品使用对POEM成功的影响尚不清楚.
研究的目的:
- 调查麻醉品使用对POEM成功率的影响.
- 为了比较患有和没有使用麻醉药物,接受POEM的患者的结果.
主要方法:
- 对90名接受POEM治疗的患者进行了回顾性单中心研究 (2017年2月至2021年9月).
- 主要结局:POEM后的埃卡德得分 (ES),抗张能力指数,手术时间.
- 二次结果:技术上的成功,肌肉切割的长度,停留时间,不良事件,重新干预,GERD.
主要成果:
- 群体之间没有人口统计学,程序时间或逗留时间的显著差异.
- 活跃的麻醉品使用者在POEM后的ES显著增加 (2.73对1.2,P=.004).
- 阻抗性指数显示,麻醉品使用者和先前未使用过阿片类药物的患者之间没有差异.
结论:
- 活跃的麻醉剂使用与POEM后症状改善较差有关.
- 麻醉剂的使用可能会对食道运动障碍的治疗成功产生负面影响.
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